Anyone who has followed it has seen huge returns. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. The SportsLine Projection Model simulates every FBS college football game 10,000 times. Before locking in any Week 5 college football picks on those games or others, be sure to see the latest college football predictions from SportsLine's advanced computer model. The Wolverines are 10.5-point favorites on the road against the unranked Iowa Hawkeyes according to the Week 5 college football lines. 4 Michigan would also love to get back into the CFP after an embarrassing 34-11 loss to Georgia in the semifinals last year. But after nearly losing as a 21-point favorite in its last road game against Texas, can you trust Alabama enough to include the Tide in your Week 5 college football bets? ET, CBS) according to the latest Week 5 college football odds from Caesars Sportsbook. 2 Alabama is a 17-point favorite on the road over No. Since the College Football Playoff was implemented in 2015, Alabama has made at least the semifinals every season but one, and the Crimson Tide will look to continue plowing towards their eight appearance in nine years when they take on the Arkansas Razorbacks on Saturday.